Jie Xu, M.S.
Project Associate

Education:

• MS - Shanghai Institute of Cell Biology, Chinese Academy of Sciences, Shanghai, P. R. China
• BS - Peking University, Department of Biology, Beijing, China

Research Experience:

• 2002-present Project Associate, Department of Veterinary Sciences, Pennsylvania State University
• 2000-2002 Senior Research Associate, Xenoport Inc., Santa Clara, CA 
• 1997-2000 Research Associate, Elan Pharmaceuticals, South San Francisco, CA
• 1995-1997 Research Associate, Dept. of Immunobiology, Yale University
• 1993-1994 Department of Molecular Genetics, University of Nijmegen, The Netherlands
• 1990-1993 Research Assistant, Shanghai Institute of Cell Biology, P. R. China 

Publications:

1. Gray AT, Zhao BB, Kindler CH, Winegar BD, Mazurek MJ, Xu J, Chavez RA, Forsayeth JR, Yost CS. Volatile anesthetics activate the human tandem pore domain baseline K+ channel KCNK5. Anesthesiology. 2000, 92(6): 1722-30.
2. Tournier C, Hess P, Yang DD, Xu J, Turner TK, Nimnual A, Bar-Sagi D, Jones SN, Flavell RA, Davis RJ. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science. 2000, 288(5467): 870-4.
3. Dong C, Yang DD, Tournier C, Whitmarsh AJ, Xu J, Davis RJ, Flavell RA. JNK is required for effector T-cell function but not for T-cell activation. Nature. 2000, 405(6782):91-4.
4. Sweileh W, Wenberg K, Xu J, Forsayeth J, Hardy S, Loring RH. Multistep expression and assembly of neuronal nicotinic receptors is both host-cell- and receptor-subtype-dependent. Brain Res Mol Brain Res. 2000, 75(2): 293-302.
5. Yang D, Tournier C, Wysk M, Lu HT, Xu J, Davis RJ, Flavell RA. Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity. Proc Natl Acad Sci U S A. 1997, 94(7): 3004-9.
6. Akhmanova AS, Bindels PC, Xu J, Miedema K, Kremer H, Hennig W. Structure and expression of histone H3.3 genes in Drosophila melanogaster and Drosophila hydei. Genome. 1995, 38(3): 586-600.
7. Tompkins, S. M., Lin, Y., Leser, G. P., Kramera, K. A., Haas, D. L. , Howerth, E. W., Xu, J., Kennett, M. J., Durbin, R. K., Durbin, J. E., Tripp, R., Lamb, R. A. and He, B. (2007) Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge. Virology. 362(1):139-50.